间隔膜的形成:从心脏计算机断层血管造影中获得的见解
Atsuko Tahara1, Sadako Motoyama1, Shaista Malik1
1Cardiology Division, School of Medicine, University of California, Irvine, Orange, California, USA.
Clinical anatomy (New York, N.Y.)
|October 11, 2024
概括
左心房隔膜囊 (LASP) 是不完全隔膜融合的一种变体,存在于三分之一的心脏中. 与 patent foramen ovale相比,LASP与较长的隔膜第二部分和重叠的隔膜第一部分有关.
科学领域:
- 心血管解剖学 心血管解剖学
- 心脏成像 - - 心脏成像
- 遗传性心脏变异 遗传性心脏变异
背景情况:
- 对于胎儿循环和成人心脏功能至关重要的心脏间隔膜,由于其组件的不完全融合,可以表现出变化.
- 左心房隔膜袋 (LASP) 是一种已知的变体,由隔膜前端和隔膜后端的不完全融合引起.
研究的目的:
- 用多探测器计算机断层扫描来评估LASP在大型队列中的患病率.
- 描述LASP, patent foramen ovale (PFO) 和完全融合隔膜 (CFS) 之间的解剖学差异.
主要方法:
- 追溯分析了864个心脏CT扫描,其中770个质量足以进行评估.
- 隔耳间隔膜变异的分类为CFS,PFO和LASP,基于隔膜前端和隔膜后端的融合.
- 定量测量隔膜第二部分的长度,隔膜第一部分的长度,重叠的隔膜第一部分,孔圆形地板尺寸和心房体积.
主要成果:
- 在31.4%的患者中,LASP被确定,PFO在23.5%中,CFS在44.0%中.
- 经过LASP的心脏表现出明显更长的隔膜第二层 (PFO的17.6毫米与13.6毫米相比) 和重叠的隔膜第一层 (PFO的13.1毫米与6.3毫米相比).
- 在隔膜第二长度和重叠的隔膜第一长度 (R2=0.28) 之间发现了正相关性.
结论:
- LASP是一种常见的心房间隔膜形态变体,约存在于三分之一的个体中.
- LASP的特点是独特的解剖学特征,包括延长的隔膜第二部分和重叠的隔膜第一部分.
- 这些发现有助于更好地了解心房间隔膜发育和变异.
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