带有哈希莫托甲状腺炎的甲状腺功能障碍儿童的甲状腺功能障碍
Gülcan Seymen1, Gözde Günay2, Ahmet Adnan Cirik2
1Department of Pediatric Endocrinology, University of Health Sciences, Umraniye Training and Research Hospital, İstanbul, Türkiye.
The journal of international advanced otology
|October 11, 2024
概括
哈西莫托甲状腺炎 (HT) 的儿童表现出前庭功能受损,特别是减少VOR增益,通过视频头部冲动测试 (vHIT) 检测到. 这表明这些患者可能存在亚临床静脉病变.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 神经学 神经学
背景情况:
- 自身免疫性甲状腺疾病,如哈西莫托甲状腺炎 (HT),与前庭功能障碍有关.
- 在患有HT的儿童中可能存在垂体末端器官问题,但需要进一步调查.
研究的目的:
- 为了分析宫引起的肌源性潜力 (cVEMP) 和视频头脉冲测试 (vHIT),与健康对照组相比,在患有HT的儿童中分析结果.
- 为了确定儿科HT患者前庭末端器官问题的患病率.
主要方法:
- 对36名患有HT的儿童和30名健康对照进行了听觉静脉检测,cVEMP和vHIT.
- 参与者被评估为正常的甲状腺功能和没有先前的前庭问题.
主要成果:
- 在HT和对照组之间,cVEMP延迟或幅度没有发现显著差异.
- 在两组之间观察到前庭眼反射 (VOR) 收益的统计学上显著差异 (P < .001).
- 80.6%的HT患者表现出较低的VOR增益 (<0.80),而健康对照只有3.3%.
结论:
- 在患有哈希莫托甲状腺炎的儿童中,可能会发生亚临床前庭病变.
- 在儿童HT患者中,vHIT是查和识别临床前前庭病理的宝贵工具.
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