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Updated: Jun 10, 2025

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两种不同剂量的德克斯梅德托米丁用于下肢手术的连续外周止痛:一项随机双盲研究

Pranjali Kurhekar1, Sam Blessy Sheba2, Sathyasuba Meenakshisundaram1

  • 1Department of Anesthesiology, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.

Journal of anaesthesiology, clinical pharmacology
|October 11, 2024
PubMed
概括

与0.5μg/kg/24h相比,在下肢手术中,连续外周用德克斯梅德托米丁1μg/kg/24h提供了优异的术后疼痛缓解. 这种较高的剂量表明改善了疼痛缓解,具有安全的血液动力学特征.

关键词:
德克斯梅德米丁的使用方法除外注 dexmedetomidine 可以引起严重的低血压. 目前尚不清楚德克斯梅德托米丁的最佳安全剂量. 在我们的研究中,我们观察到连续外周输注1μg/kg/24小时的德克斯梅德托米丁可以在可接受的血液动力学变化下提供更好的止痛.外围注射止痛 止痛 止痛剂血液动力学稳定性 血液动力学稳定性罗皮瓦卡因 (ropivacaine) 是一种可怕的药物.

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