莱姆神经病中的感觉神经听力损失
Elisa Skovgaard Jensen1, Per Cayé-Thomasen2,3, Jacob Bodilsen4
1Department of Otorhinolaryngology, Nordsjællands Hospital, University of Copenhagen, Hillerød, Denmark.
Annals of medicine
|October 11, 2024
概括
莱姆病神经病变 (LNB) 可能会导致由于耳功能障碍而导致神经感官听力损失 (SNHL). 虽然一些听力功能可能会恢复,但长期的SNHL是可能的.
科学领域:
- 耳神经病学 耳神经病学
- 传染性疾病 传染性疾病
- 听力学 听力学是指听力学.
背景情况:
- 感觉神经听力损失 (SNHL) 是莱姆神经病 (LNB) 的潜在并发症.
- 此前还没有确定LNB和SNHL之间的最终关联.
- 这项研究前性地评估了LNB患者的SNHL,使用扭曲产品-音响发射 (DPOAE).
研究的目的:
- 调查诊断为LNB.患者的SNHL的发生率和进展情况.
- 用DPOAE测量评估LNB患者的耳功能.
- 为了确定LNB是否导致暂时或长期听力损伤.
主要方法:
- 在入院时测量了25名LNB患者和随访时测量了18名LNB患者的扭曲产品-音响排放 (DPOAE).
- 在出院和出院后60天进行纯色音量计 (PTA3).
- 患者接受了标准的14天静脉注射塞夫triaxone或口服多西环林治疗.
主要成果:
- 在78%的患者中,在低,中,中高频率下观察到DPOAE排放值 (ETL) 的改善.
- 在高频类别中注意到ETL的下降.
- 排放时SNHL (PTA3>20dB) 存在于48%和排放后60天的56%,与对照群明显不同.
结论:
- 莱姆神经病可以导致耳外毛细胞功能障碍.
- 这种功能障碍可以导致暂时和持续的感觉神经神经听力损失.
- 这些发现确定了LNB和SNHL之间的联系,强调了需要进行听觉监测的必要性.
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