与沙特阿拉伯糖尿病前期发展相关的特征和危险因素
Ayla M Tourkmani1, Turki J Alharbi1, Abdulaziz M Bin Rsheed1
1Chronic Illness Clinics, Department of Family and Community Medicine, Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia.
Annals of medicine
|October 11, 2024
概括
在沙特阿拉伯,糖尿病前期很常见. 确定的主要危险因素包括年龄,男性性别,肥胖,高血压,心脏病和多囊性卵巢综合征,突出了针对性预防策略的领域.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 糖尿病前期代表着一个重要的全球健康问题,沙特阿拉伯的患病率很高.
- 它是2型糖尿病的关键前体,与许多不良健康结果和并发症有关.
- 确定特定的风险因素对于在该地区制定有效的公共卫生干预措施至关重要.
研究的目的:
- 调查和确定与沙特阿拉伯人口中糖尿病前期发展相关的独立风险因素.
- 提供数据,可以为沙特阿拉伯的糖尿病前期的有针对性的预防和管理策略提供信息.
主要方法:
- 在利雅得苏丹王子军事医疗城进行了一项病例控制研究,涉及46,201名参与者.
- 该研究包括16029名被诊断为糖尿病前期患者 (病例) 和30173名正常HbA1c水平的人 (对照组).
- 收集的数据包括社会人口统计信息,临床参数,实验室结果和现有医疗条件,使用多重物流回归分析.
主要成果:
- 该研究确定了前糖尿病的六个独立风险因素:年龄 (aOR=1.067),男性性别 (aOR=0.695女性),多囊卵巢综合征 (aOR=58.102),肥胖 (aOR=1.265),心脏病 (aOR=4.870) 和高血压 (aOR=1.133).
- 与对照组相比,糖尿病前期患者年龄大 (47.22±14.04岁),BMI (33.76±6.75) 较高.
- 在糖尿病前期组中观察到更高比例的男性.
结论:
- 一些可修改和不可修改的因素显著增加沙特人口糖尿病前期风险.
- 针对已确定的风险因素,如肥胖,高血压和PCOS等特定疾病,对于预防糖尿病前期至关重要.
- 有效的干预措施可以减轻沙特阿拉伯日益增长的糖尿病前期和糖尿病进展的负担.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
512
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
512
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Pathophysiology of Diabetes
881
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
881
Coronary Artery Disease I: Introduction
3
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
3
Diabetes Mellitus: Overview and Type I Subtype
2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Psychoneuroimmunology: Diabetes and Cancer
24
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
24


