鼻腔连续正气道压力立即抽出口腔后,用于预防早产婴儿的发病率
Jacqueline J Ho1, Anna M Kidman2, Brady Chua3
1Department of Paediatrics, RCSI & UCD Malaysia Campus (formerly Penang Medical College), George Town, Malaysia.
The Cochrane database of systematic reviews
|October 11, 2024
概括
鼻腔连续正气道压力 (NCPAP) 可以减少早产婴儿的输出失败. 这种干预措施在侵入性通风后应用,显示了潜在的益处,但需要进一步调查再输管和支气管肺功能失调风险.
科学领域:
- 新生儿护理 新生儿护理
- 呼吸系统的支持呼吸系统的支持
- 基于证据的医学是基于证据的医学.
背景情况:
- 从侵入性通风中抽出管道的早产婴儿面临呼吸衰竭和再输管的风险.
- 传统的方法,如头箱氧气或鼻腔管可能是不够的.
- 非侵入性压力支可以通过稳定气道和肺功能来改善输出成功.
研究的目的:
- 评估鼻腔连续正气道压力 (NCPAP) 是否降低了早产婴儿的输出失败.
- 评估是否需要额外的通风器支持.
- 为了确定NCPAP是否会导致临床上显著的不良事件.
主要方法:
- 随机对照试验的系统审查和元分析.
- 搜索了CENTRAL,MEDLINE,Embase和试验登记册,截至2023年9月.
- 包括从侵入性通风中输出输管的早产婴儿,比较NCPAP与没有CPAP (头箱氧气,室内空气等). ) 的情况.
主要成果:
- NCPAP可能会减少输出失败 (低确定性证据) 和潜在的重新输入 (非常低确定性证据).
- 治疗NCPAP以防止一次输出失败所需的数量是6.
- 证据表明NCPAP对支气管肺功能障碍的影响是不确定的;没有报告神经发育结果.
结论:
- 在输出管后立即应用NCPAP可能会改善早产婴儿的输出管成功.
- 关于其对再输管和支气管肺功能障碍症的影响仍然存在不确定性.
- 尽管证据的确定性很低,但NCPAP被认为是标准实践,否定了进一步研究的需要.
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