Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

2.1K
Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
2.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Stepwise mitochondria-targeted photodynamic immunotherapy enabled by an outer membrane vesicles-based nanoplatform for synergistic tumor ablation and immune reprogramming.

Smart molecules : open access·2026
Same author

Sema4A Protects Against Muscle Atrophy and Promotes Repair by Regulating Intracellular Metabolic Signalling.

Journal of cachexia, sarcopenia and muscle·2026
Same author

Thyroid autoimmunity in relation to islet autoantibodies in newly diagnosed type 1 diabetes mellitus in children and adolescents.

Frontiers in endocrinology·2026
Same author

A Novel Dual-Gradient Patterned Wettability Current Collector for Passive DMFCs.

Nanomaterials (Basel, Switzerland)·2026
Same author

Covalently photosensitized probiotic bacteria for light-triggered tumor clearance and self-limiting immunotherapy.

Biomaterials·2026
Same author

Smart Sonoafterglow Nanobombs for High-Contrast Imaging and Synergistic Gas-Sonodynamic Therapy of Hypoxic Tumors.

Angewandte Chemie (International ed. in English)·2026
Same journal

Multifunctional polysulfone/strontium silicate composites with tunable properties through silane functionalization.

Journal of materials chemistry. B·2026
Same journal

Melanocortin 1 receptor-targeted peptide-functionalized liposomes for enhanced melanocyte-preferential drug delivery and anti-melanogenic efficacy.

Journal of materials chemistry. B·2026
Same journal

Recent progress in side-chain amino acid-based polymers: synthesis, self-assembly, and emerging biomedical applications.

Journal of materials chemistry. B·2026
Same journal

Bioinspired electrospun nanofibrous dressings loaded with Mentha-derived exosome-like vesicles for antibacterial and immunomodulatory burn healing.

Journal of materials chemistry. B·2026
Same journal

On demand functionality of an NIR-enhanced nanozyme catalyst for infected wound healing.

Journal of materials chemistry. B·2026
Same journal

Positively charged, phenolic hydroxyl and anthraquinone structured polystyrene microspheres targeting dual elimination of bacterial pathogens and pathogen-associated molecular patterns for sepsis therapy.

Journal of materials chemistry. B·2026
查看所有相关文章

相关实验视频

Updated: Jun 10, 2025

Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells
11:06

Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells

Published on: June 30, 2018

8.4K

由人工智能驱动的精确亚细胞导航使用光探测器.

Yingli Zhu1, Yanpeng Fang1, Wenzhi Huang1

  • 1Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, P. R. China. jiedong@csu.edu.cn.

Journal of materials chemistry. B
|October 11, 2024
PubMed
概括
此摘要是机器生成的。

人工智能 (AI) 彻底改变了光探测器开发,用于精确的细胞导航和疾病诊断. 人工智能优化探头设计,增强光学性能和针对高级生物医学应用的定位能力.

更多相关视频

Single-Molecule Imaging of Nuclear Transport
12:13

Single-Molecule Imaging of Nuclear Transport

Published on: June 9, 2010

13.3K
Author Spotlight: Advanced Techniques for Visualizing Endogenous Axonal Transport Dynamics
05:47

Author Spotlight: Advanced Techniques for Visualizing Endogenous Axonal Transport Dynamics

Published on: February 16, 2024

711

相关实验视频

Last Updated: Jun 10, 2025

Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells
11:06

Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells

Published on: June 30, 2018

8.4K
Single-Molecule Imaging of Nuclear Transport
12:13

Single-Molecule Imaging of Nuclear Transport

Published on: June 9, 2010

13.3K
Author Spotlight: Advanced Techniques for Visualizing Endogenous Axonal Transport Dynamics
05:47

Author Spotlight: Advanced Techniques for Visualizing Endogenous Axonal Transport Dynamics

Published on: February 16, 2024

711

科学领域:

  • 生物医学工程 生物医学工程
  • 化学生物学 化学生物学
  • 计算生物学 计算生物学

背景情况:

  • 生物系统内的精确导航对于理解细胞功能和诊断疾病至关重要.
  • 光分子探针是针对特定生物分子的重要工具.
  • 目前的探测器开发在实现高精度和有效性方面面临限制.

研究的目的:

  • 探索人工智能 (AI) 在设计先进的光分子探测器方面的变革潜力.
  • 详细介绍AI在优化探测器物理化学和光学性能方面的作用,以提高目标.
  • 要突出人工智能驱动的进步及其对亚细胞研究,诊断和药物发现的影响.

主要方法:

  • 利用人工智能算法,通过优化物理化学性质来设计新的亚细胞染料.
  • 采用人工智能来设计基于特定受体相互作用的目标亚细胞探针.
  • 应用人工智能对规范光分子的化学规律进行定量分析,以优化光学性能.
  • 利用人工智能进行全面的探测器属性优化,并指导构建多功能探测器.

主要成果:

  • 展示AI设计高精度和有效的光探测器的能力.
  • 展示了近期人工智能驱动的探测器开发方面的进展.
  • 突出了人工智能设计的探针的成功生物医学应用.
  • 识别人工智能辅助探头设计中的关键挑战和未来研究方向.

结论:

  • 人工智能显著提高了光分子探针的设计和优化.
  • 人工智能驱动的探测器显示出革命性的潜细胞研究,诊断和药物发现的巨大前景.
  • 持续开发人工智能对于推进分子成像和向治疗领域至关重要.