管理儿童的CDH1癌症风险:在患有遗传扩散性胃癌的家庭中做出复杂的决策
Nihat Bugra Agaoglu1,2,3, Ozden Hatirnaz Ng4,5,6, Itir Ebru Zemheri7
1Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
American journal of medical genetics. Part A
|October 11, 2024
概括
生殖系CDH1致病变体 (PVs) 可以导致遗传性扩散性胃癌. 这项研究强调了在患有CDH1PV和家族病史的儿童中管理胃癌风险的挑战.
科学领域:
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
- 胃肠病学 胃肠病学
背景情况:
- CDH1基因中的生殖系致病变体 (PVs) 与遗传性扩散性胃癌 (HDGC) 有关.
- 对于CDH1 PVs和胃癌家族史的个体的管理策略包括预防性全胃切除术或密集监测协议.
- 早期发病的胃癌带来了重大的临床和家庭挑战.
关键词:
CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1青少年 青少年 青少年 青少年扩散性胃癌是一种扩散性胃癌.儿科 儿科 儿科年轻的成年人年轻的成年人更多相关视频
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