大麻素在手部病理的疼痛管理中的患病率和影响
Marc G Sleiman1, Andrew Straszewski2, Jeffrey G Stepan2
1The University of Chicago, IL, USA.
概括
15%的城市手病患者使用大麻素来缓解疼痛. 这些化合物提供与传统药物相似的疼痛缓解,并且患者同样或更喜欢这些化合物.
科学领域:
- 整形外科手术 整形外科手术
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 大麻素正在研究其止痛特性.
- 由于使用变化,了解大麻素在疼痛管理中的流行程度至关重要.
- 专注于城市骨科手患者提供了特定的临床背景.
研究的目的:
- 分析大麻素在城市骨科手患者的疼痛管理中使用的大麻素的普遍性.
- 与传统止痛药相比,评估大麻素在减轻疼痛方面的有效性.
- 评估患者对大麻素的偏好与处方/非处方 (Rx/OTC) 药物的偏好.
主要方法:
- 在一个城市学术医院的骨科手部诊所,向122名新患者分发了一份电子调查.
- 收集的数据包括人口统计,疼痛评分 (数值评分表),大麻素使用和其他疼痛管理策略.
- 分析了使用前和后的疼痛评分,以确定止痛作用.
主要成果:
- 15% (18/122) 的患者报告使用大麻素治疗手部疼痛.
- 大麻素和Rx/OTC药物都显著降低了疼痛评分 (分别P = .002和P < .001).
- 大麻素显示出更大的疼痛减轻趋势 (Δ4.4 vs Δ3.0),尽管在统计学上不显著 (P = .06). 患者偏好青大麻素或与传统选择相等.
结论:
- 大约15%的城市手病患者使用大麻素来控制疼痛.
- 大麻素的止痛效果与手部病理的Rx/OTC药物具有相似的效果.
- 患者喜欢或喜欢大麻素,这表明大麻素在手部疼痛管理中起着重要作用.
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