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Updated: Jun 10, 2025

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在活细胞中本地同定位的G4s和R循环的全基因组映射

Ting Liu1, Xing Shen1, Yijia Ren1

  • 1Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, Department of Pediatrics, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, China.

eLife
|October 11, 2024
PubMed
概括

原生G四重复结构 (G4s) 和R环对于DNA调节至关重要. 这项研究绘制了它们在细胞中的共同定位图,揭示了动态模式,并确定了Dhx9作为影响基因转录和细胞功能的关键调节者.

关键词:
在 Dhx9 的位置上.在HBD-seqq.在HepG4-seqq.在R-Loop中使用.生物化学 生物化学化学生物学 化学生物学同定位的G4s.遗传学 遗传学 遗传学 是一个基因组学就是基因组学.人类 人类 人类 人类 人类 人类 人类这里是鼠标鼠标鼠标鼠标鼠标鼠标.原生G-四重复合体原生R-循环是原生的

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