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Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis.
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Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large...
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The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
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核补偿进化是由线粒细胞核不兼容性驱动的.

Debora Princepe1, Marcus A M de Aguiar1

  • 1Departamento de Física da Matéria Condensada, Instituto de Física Gleb Wataghin, Universidade Estadual de Campinas (UNICAMP), Campinas 13083859, Brasil.

Proceedings of the National Academy of Sciences of the United States of America
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PubMed
概括
此摘要是机器生成的。

线粒体和核基因协调是细胞功能的关键. 这项研究揭示了遗传不相容性如何推动进化变化,影响物种辐射和共同进化.

关键词:
线粒细胞核共同进化线粒体突变率的发生率.在 mtDNA 内进的过程中.核补偿的核补偿是什么意思

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科学领域:

  • 进化生物学是进化的生物学.
  • 遗传学 遗传学 是一个
  • 分子生物学分子生物学

背景情况:

  • 线粒体功能取决于协调的核和线粒体基因表达.
  • 高的线粒体突变率是通过核补偿机制被容忍的.
  • 线粒核兼容性的流行率和驱动因素仍在争论中.

研究的目的:

  • 为了研究线粒核不相容性对物种辐射期间遗传替代的影响.
  • 模拟线粒核协调的选择如何影响基因组进化.
  • 了解线粒体内进化的物种化中的作用.

主要方法:

  • 开发了一个种群遗传学模型,模拟来自部分兼容的线粒核状态的物种辐射.
  • 嵌入的遗传兼容性,空间接近性和生育能力下降与不兼容性.
  • 分析了不同线粒体突变率和初始基因组状态对进化轨迹的影响.

主要成果:

  • 线核兼容性的选择对核和线粒体基因组产生不同影响.
  • 不兼容的核基因始终促进补偿性突变.
  • 高的线粒体突变率可以降低核补偿,但可以促进相容的核基因中的替代.
  • 线核不兼容性加速物种辐射,但与平衡物种丰富性没有直接相关.

结论:

  • 线粒核不相容性在驱动物种辐射和共同进化方面发挥着重要作用.
  • 核补偿的动态是复杂的,受到突变率和初始基因组相容性的影响.
  • 识别特定的基因组特征对于检测这些进化过程至关重要.