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使用iStent inject®植入物在窄角玻璃眼中进行发泡乳液的长期结果
Z Cheng1, T Berman1, A Choudhary1
1Royal Liverpool University Hospital, St Paul's Eye Unit, Prescot Street, Liverpool L7 8XP, UK.
Journal francais d'ophtalmologie
|October 11, 2024
概括
使用iStent注射的法化可以安全有效地降低眼内压力 (IOP),并减少狭视角玻璃眼 (NAG) 患者的药物需求. 这种外科选择表明显著的长期IOP控制和低的重复玻璃眼外科手术率.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- MIGS (最小侵入性玻璃眼外科手术)
背景情况:
- 窄角玻璃眼 (NAG) 是由于眼内压力升高 (IOP) 造成视力损失的重大风险.
- 有效的IOP管理对于预防光眼神经病变的进展至关重要.
- 加上微侵袭性玻璃眼外科手术 (MIGS) 的法科化为NAG管理提供了一个潜在的解决方案.
研究的目的:
- 评估使用iStent注射植入物 (phaco-iStent) 进行化剂的疗效和安全性,用于诊断为NAG的患者.
- 评估法科-iStent对眼内压力 (IOP) 的影响以及对青光眼药物的需求.
- 确定与NAG管理中的phaco-iStent相关的长期结果和并发症率.
主要方法:
- 一项回顾性临床队列研究对接受了法科-iStent手术的NAG患者进行.
- 来自手术结果数据库的数据分析了57只眼睛的数据,平均随访时间为32个月.
- 主要结局包括平均内血压和药物使用的变化,成功指的是特定的内血压值 (≤21mmHg或≤15mmHg),有或没有滴.
主要成果:
- 平均内血压从手术前的19.7±4.2mmHg显著下降到手术后12,24和36个月的14.0-14.9mmHg.
- 在最后一次随访中,绿眼瘤药物的平均数量从2.2±0.7减少到0.92±1.24.
- 在37-49%的眼睛中取得了完全成功 (IOP ≤21mmHg无滴),而在36个月后,合格的成功 (IOP ≤21mmHg含滴) 超过92%. 对于IOP ≤15mmHg的合格成功率在36个月后达到了54%. 只有5%的患者需要进一步的绿眼瘤手术.
结论:
- 使用iStent注射植入物进行法化是一种安全有效的手术干预,用于管理狭角玻璃眼 (NAG).
- 该程序导致眼内压力和药物依赖的显著和持续降低.
- 在NAG患者中,Phaco-iStent具有良好的安全性,长期并发症最小.
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