相关实验视频

Updated: Jun 10, 2025

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

微侵袭性玻璃眼瘤手术中的种族差异用于初级开放角度玻璃眼瘤的管理:一种倾向匹配的队列研究

Pranav Vasu¹, Rigel P Hall¹, Isabella V Wagner²

¹From the Department of Medicine, Creighton University School of Medicine (P.V., R.P.H.), Phoenix, Arizona.

American journal of ophthalmology

|October 11, 2024

概括

患有初级开角玻璃眼 (POAG) 的非裔美国患者接受微创性玻璃眼手术 (MIGS) 的频率低于非非裔美国患者. 这项研究表明,在美国的POAG管理中存在潜在的种族差异.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
健康差异在健康上的差异

背景情况:

主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
已知POAG在非洲裔美国人中更为普遍.
微侵入性玻璃眼外科手术 (MIGS) 为玻璃眼管理提供了一种不那么侵入性的外科选择.

研究的目的:

调查在美国用于轻度至中度初级开角青光眼 (POAG) 的微侵袭性青光眼手术 (MIGS) 的种族和民族差异.
根据种族来确定POAG手术管理中的潜在差异.

主要方法:

使用TrinetX数据库进行回顾性队列研究.
包括被诊断患有轻度或中度POAG的患者.
非洲裔美国人和非非洲裔美国人群之间的人口统计和临床因素的倾向性得分与控制相匹配.
在POAG诊断后一年内分析MIGS发病率.

主要成果:

总共有63,418名POAG患者被分析 (50%的非裔美国人,50%的非非裔美国人).
与非非裔美国患者相比,非裔美国患者的MIGS发病率明显较低 (OR 0.834,95%CI 0.773-0.900).

结论:

尽管在非洲裔美国人中POAG的流行率较高,但他们使用MIGS的比例较低.
研究结果表明,在初级开角青光眼的手术治疗中,可能存在全国性的种族差异.
进一步的研究是有必要的,以了解和解决这些差异在眼的护理.

更多相关视频

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

相关概念视频

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...