多会话tDCS与内刺激训练相结合,改善了自闭症谱系障碍青少年的情绪识别
Karin Prillinger1, Gabriel Amador de Lara1, Manfred Klöbl2
1Department of Child and Adolescent Psychiatry, Medical University of Vienna, 1090 Vienna, Austria; Comprehensive Center for Pediatrics (CCP), Medical University of Vienna, 1090 Vienna, Austria; Comprehensive Center for Clinical Neuroscience and Mental Health (C3NMH), Medical University of Vienna, 1090 Vienna, Austria.
概括
跨直流刺激 (tDCS) 与社会认知训练相结合,在患有自闭症谱系障碍 (ASD) 的青少年中显著改善了动态情绪识别. 这种新的方法显示出增强自闭症社会意识的希望.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 自闭症谱系障碍 (ASD) 在社会认知方面存在挑战.
- 跨直流刺激 (tDCS) 是一种新兴的ASD治疗方法.
- 目前,对于ASD没有存在内刺激社会认知培训协议.
研究的目的:
- 研究结合阳极tDCS与ASD青少年的新型内刺激社会认知训练的疗效.
- 评估这种联合干预对情绪识别和整体ASD症状的影响.
主要方法:
- 这是一项双臂,双盲,随机,假控制的试验,涉及22名患有自闭症的男青少年.
- 在线情绪识别任务配对的无极或虚拟tDCS的10次会议.
- 模拟单个电场分布,并分析大脑激活模式.
主要成果:
- 与假装的tDCS相比,阳道tDCS显著增强了动态情绪识别.
- 培训任务引起了面部加工地区的高度激活.
- 与中部前额叶皮质的电场密度相关的改善以及社会意识.
结论:
- 多会话tDCS与有针对性的社会认知培训相结合,有效地改善了ASD青少年的动态情绪识别.
- 干预活动激活社会大脑网络中的关键区域.
- 由于电场变化,可能需要个性化tDCS方法来优化治疗效果.
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