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Updated: Jun 10, 2025

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系统性硬化症中的听觉受体症状:系统性审查和元分析
Craig D Salvador1, Brian A Keith1, Celine Ward1
1Medical University of South Carolina, 135 Rutledge Ave, Charleston, SC, 29425, USA.
概括
患有全身性硬化症 (SSc) 的患者比对照患者更容易出现耳,头和听力损失. 虽然在统计学上显著,但这些听力学和前庭问题可能在临床上并不显著,因此需要进一步评估.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 类风湿病学 类风湿病学
- 系统性硬化症研究研究
背景情况:
- 系统性硬化症 (SSc) 是一种复杂的自身免疫性疾病,可能涉及多个器官.
- 听觉静脉病理越来越被认为是SSc患者的并发症.
- 了解这些症状的流行和表现对于患者管理至关重要.
研究的目的:
- 为了确定患有全身性硬化症 (SSc) 的患者与非SSc患者相比,听觉静脉病理的患病率更高.
- 在SSc.中对听觉口腔问题的症状和基于测试的呈现进行表征.
- 回答PICO关于SSc.中的听觉静脉病理学的问题.
主要方法:
- 一项系统性审查和对2023年11月27日之前发表的研究进行元分析.
- 搜索了包括PubMed,Scopus,CINAHL和Cochrane图书馆在内的数据库.
- 包括SSc患者和听觉静脉症状的研究;排除了没有相关结果或少于四名患者的研究.
主要成果:
- 分析了13项涉及414名SSc患者和390名对照者的研究.
- 与对照组相比,SSc患者报告的耳 (34.1%),头 (32.4%) 和主观听力损失 (26.0%) 的比率明显更高.
- 由于报告不完整,前庭检测数据不足以进行元分析.
结论:
- 与对照组相比,全身性硬化症患者表现出统计学上显著的,但不是临床上显著的听力损伤.
- 在SSc患者中主观听力学和前体症状的增加凸显了跨学科护理的需要.
- 在适当的临床背景下,应考虑在SSc患者中评估听觉静脉病理.
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