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Updated: Jun 10, 2025

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
07:08

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Published on: February 27, 2018

9.5K

m6 突变的亨廷丁RNA的修饰促进了致病性亨廷丁转录的生物发生

Anika Pupak1,2,3, Irene Rodríguez-Navarro1,2,3, Kirupa Sathasivam4

  • 1Departament de Biomedicina, Facultat de Medicina, Institut de Neurosciències, Universitat de Barcelona, Barcelona, Spain.

EMBO reports
|October 11, 2024
PubMed
概括

亨廷顿病 (HD) 涉及异常的亨廷丁 (HTT) mRNA处理. 这项研究表明,在扩大CAG重复的影响下,Htt 内子1中的m6A甲基化调节了致病性HTT1a转录水平.

关键词:
HTT1a 在线阅读亨廷顿氏病是亨廷顿氏病的一种疾病.编辑RNA编辑RNA编辑拼接 拼接 拼接 拼接m6A 一个很好的.

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Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System10:52

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Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy11:22

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

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