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Updated: Jun 10, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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Published on: August 12, 2018

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脂质过氧化产品诱导碳酸应激,线粒体功能障碍,以及人类和小鼠细胞的细胞衰老

T Blake Monroe1, Ann V Hertzel1, Deborah M Dickey1

  • 1Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA.

Aging cell
|October 12, 2024
PubMed
概括

生物性脂质酶,如4-HNE,通过破坏DNA和蛋白质,触发细胞衰老. 这个被称为生物性脂质诱导衰老 (BLIS) 的过程,将氧化应激与与年龄相关的疾病联系起来.

关键词:
4-HNE 4 -HNE 是一个很好的选择.脂肪的脂肪的脂肪脂质过氧化过氧化这是线粒体的线粒体.衰老是一种老化.

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