精子形态参数在选择受精方法中的作用
Donghong Li1, Yunhao Wang1, Longling Han1
1Department of Reproductive Medicine, The Maternal and Child Health Hospital of Changde City, 415000 Changde, Hunan, China.
Revista internacional de andrologia
|October 12, 2024
概括
试管婴儿 (IVF) 和细胞内精子注射 (ICSI) 是有效的治疗子精症. 有时需要救援ICSI (R-ICSI),但中度和重度病例的结果相似.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 胚胎学 胚胎学
背景情况:
- 以异常的精子形态为特征的teratozoospermia是男性不孕症的常见原因之一.
- 对于孤立的特拉精子症的最佳辅助生殖技术 (ART) 策略仍在争论中.
研究的目的:
- 为了评估体外受精 (IVF) 与细胞内质精子注射 (ICSI) 的疗效,在患有隔离性高精子症的患者中.
- 为了比较胚胎学结果和中度和重度精子群之间的救援ICSI (R-ICSI) 的需要.
主要方法:
- 在2018-2022年间进行IVF/ICSI的81对患有隔离性精子症的夫妇的回顾性分析.
- 胚胎学数据的比较,包括囊胚发育和R-ICSI率,在中度和严重的三种子精群之间.
主要成果:
- 在中度 (18.33%) 和重度 (14.29%) 类精子群之间,R-ICSI率没有统计学上显著的差异.
- 胚胎学结果,如囊胚发育,在两组之间没有显著差异.
- 试管婴儿对中度和重度的三种子精有效,根据需要使用R-ICSI.
结论:
- 患有中度和重度隔离性三种子精的患者可以通过试管婴儿进行有效管理.
- 在这些患者体外受精期间发生受精失败时,救援ICSI (R-ICSI) 是一种可行的选择.
- 这项研究为不育患者在选择适当的精计划时提供了参考.
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