打破障碍:通过向NLRP3炎症酶来克服癌症耐药性

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Updated: Jun 10, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

Published on: May 21, 2018

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Nazanin Pazhouhesh Far1, Mahsa Hajiheidari Varnousafaderani2, Ferdos Faghihkhorasani3

  • 1Department of Microbiology, Faculty of Advanced Science and Technology, Tehran Medical Science, Islamic Azad University, Tehran, Iran.

British journal of pharmacology
|October 12, 2024
PubMed
概括

炎症通过促进转移和入侵驱动癌症. NOD-Like受体蛋白3 (NLRP3) 炎症酶在这些过程中发挥着关键作用,并为癌症治疗提供了潜在的治疗点.

关键词:
这就是CRISPR/Cas9的作用.针对癌症的向治疗.免疫检查点抑制剂 免疫检查点抑制剂热致灭 (pyroptosis) 是一种致的过程.瘤微环境 (TME) 是一种微环境.

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