后生物质的抗氧化特性:对分析和评估方法的概述
Negin Hosseinzadeh1,2, Abolfazl Asqardokht-Aliabadi3, Vahideh Sarabi-Aghdam4
1Student Research Committee, Department of Food Science and Technology, Tabriz University of Medical Sciences, Tabriz, Iran. Hosseinzadeh@tbzmed.ac.ir.
Probiotics and antimicrobial proteins
|October 12, 2024
概括
后生物质为合成抗氧化剂提供了安全,天然的替代品,对健康和工业有很大的前景. 这篇评论强调使用基于细胞的测试,如Caco-2,以有效评估后生物抗氧化剂活性和生物可用性.
科学领域:
- 食品科学与技术 食品科学与技术
- 微生物学 微生物学
- 生物化学 生物化学
背景情况:
- 自然抗氧化剂可以预防疾病,但合成抗氧化剂会引起健康问题 (肝病,癌症).
- 后生物质,即益生菌发酵的化合物,表现出抗氧化,抗菌,抗炎和抗癌的特性.
- 目前评估抗氧化剂活性的方法存在局限性,需要采用更具生物学相关性的方法.
研究的目的:
- 突出后生物质作为合成抗氧化剂的安全替代品.
- 审查评估后生物抗氧化活性的方法.
- 强调基于细胞的测试对评估后生物效能的重要性.
主要方法:
- 复习现有的关于后生物质和抗氧化剂评估的文献.
- 专注于基于细胞的测试,特别是Caco-2细胞系.
- 细胞抗氧化活性 (CAA) 和生物可用性的分析.
主要成果:
- 后生物体显示出作为天然抗氧化剂的巨大潜力.
- 基于细胞的测试提供了体外和体内研究之间的关键联系.
- 卡科-2细胞系是评估后生物抗氧化作用的宝贵工具.
结论:
- 后生物质是食品和药品中合成抗氧化剂的可行的替代品.
- 过渡到基于细胞的测试对于准确评估后生物抗氧化活性至关重要.
- 了解加工对后生物质的影响可以推动产品开发的创新.
相关概念视频
01:20Radical Autoxidation
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
01:22Probiotics
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...