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Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry
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3D打印涂层刀片喷雾质谱仪器件 3D打印涂层刀片喷雾质谱仪器件

Wei Zhou1, Qizhen Lan1, Malvika Dutt1

  • 1Department of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.

Analytical chemistry
|October 12, 2024
PubMed
概括

3D打印使涂层叶片喷雾质谱 (CBS-MS) 的用户友好的解决方案成为可能. 新的接口和提取设备加速了血液和尿液等生物样本中微量化合物查.

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Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
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