在水生环境中,ractopamine的直接和间接光降解机制
Weiming Xiang1, Dong Wan2, Wentao Zhou1
1School of Environmental Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, PR China.
研究了拉科巴胺 (RAC) 在水中的光降解. 直接和间接的途径被确定,受pH,DOM和铜离子的影响,揭示了RAC的环境命运.
科学领域:
- 环境化学环境化学
- 摄影化学的使用.
- 水生毒理学 水生毒理学
背景情况:
- 拉科巴胺 (RAC) 是一种经常在农业下水中检测到的兽药药物.
- 它的存在对水生生态系统和人类健康构成风险.
- RAC的环境命运和退化途径尚未得到充分理解.
研究的目的:
- 在紫外线照射下研究RAC的直接和间接光降解机制.
- 为了确定环境因素 (pH,DOM,金属离子) 对RAC光降解的影响.
- 阐明参与RAC去除的光化学途径和反应物种.
主要方法:
- 紫外线照射 (275和365纳米) 的实验.
- 在不同pH,DOM和Cu2+度下分析RAC降解动力学.
- 电子自旋共振 (ESR) 光谱和火实验以确定反应性物种.
- 液体染色学-双重质谱学 (LC-MS/MS) 用于产品识别.
- 密度函数理论 (DFT) 用于分子轨道和福井指数的计算分析.
主要成果:
- RAC的直接光降解量子收益率随着pH的增加而增加.
- 间接光降解被DOM增强并增加了pH.
- 铜离子 (Cu2+) 抑制了直接和间接的RAC光降解.
- RAC光降解主要涉及类组的氧化和脱碳.
- 反应性物种包括RAC三重状态,DOM三重状态 (3DOM*) 和单氧.
结论:
- 光降解是水生环境中RAC去除的重要途径.
- 像pH和DOM组成这样的环境因素极大地影响RAC的光化学命运.
- 了解这些机制对于评估和减轻RAC的环境风险至关重要.
更多相关视频
13:12Nitroreductase/Metronidazole-Mediated Ablation and a MATLAB Platform RpEGEN for Studying Regeneration of the Zebrafish Retinal Pigment Epithelium
Published on: March 2, 2022
08:46Dose Uptake of Platinum- and Ruthenium-based Compound Exposure in Zebrafish by Inductively Coupled Plasma Mass Spectrometry with Broader Applications
Published on: April 21, 2022
相关概念视频
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Indirect-Acting Cholinergic Agonists: Mechanism of Action
Reversible inhibitors like edrophonium bind to a specific part of the enzyme called the anionic catalytic site. They form noncovalent bonds, which means they are not strongly attached to the enzyme. This creates a temporary and less stable enzyme–inhibitor complex,...
Channel Rhodopsins
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
Indirect-Acting Cholinergic Agonists: Pharmacokinetics
Reversible agents containing quaternary amines, such as neostigmine and edrophonium, are not easily absorbed orally because they...
Direct-Acting Cholinergic Agonists: Pharmacokinetics
Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...
