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Updated: Jun 12, 2025

Characterization of G Protein-coupled Receptors by a Fluorescence-based Calcium Mobilization Assay
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Published on: July 28, 2014

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在HEK293细胞中,GPCR介导的Ca2+调动激活的各种途径

Francesco De Pascali1, Asuka Inoue2, Jeffrey L Benovic1

  • 1Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

The Journal of biological chemistry
|October 12, 2024
PubMed
概括

G蛋白结合受体 (GPCRs) 调解细胞反应. 这项研究揭示了Gs合受体的独特途径,如β2-上腺素受体 (β2AR),EP2和EP4受体,以在HEK293细胞中调动 (Ca2+).

关键词:
在Ca2+) 调动过程中,与G蛋白结合受体的受体是G蛋白结合受体.异构三元的G蛋白质.的前列腺素E受体.在β(2) - 上腺素受体.

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