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Updated: Jun 12, 2025

Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes
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脂治疗的分子决定因素,以减少NPC1缺陷中的细胞内胆固醇积累

Shikun Deng1, Ting-Ann Liu1, Olga Ilnytska2

  • 1Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA.

The Journal of biological chemistry
|October 12, 2024
PubMed
概括

Lysobisphosphatidic 酸 (LBPA) 在尼曼-皮克型C (NPC) 疾病模型中有效降低胆固醇积累. 特定的LBPA结构,特别是那些具有18:1乙链的结构,对于这种胆固醇清除效果至关重要.

关键词:
尼曼-皮克C型疾病双单基甘油酸二氧化-monoacylglycerol酸胆固醇 胆固醇 胆固醇 是一种lysobisphosphatidic 酸 的作用是什么lysosome 溶解酶体是如何形成的酸糖醇是酸的原料之一.脂酸是一种脂酸.

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