癌症诊所后的专门更年期可能会改善对乳腺癌内分泌疗法的坚持:一项基于人口的研究
Hilary Martin1, Christobel Saunders2, Andrew Redfern1
1Medical Oncology Department, Fiona Stanley Hospital, Western Australia, Australia; School of Medicine, University of Western Australia, Western Australia, Australia.
Clinical breast cancer
|October 12, 2024
概括
专门的更年期诊所可以改善乳腺癌患者的内分泌疗法坚持,这些患者经历了严重的热. 虽然在统计学上不显著,但在癌症诊所 (MSAC) 后经过更年期症状管理的妇女的停药率较低.
科学领域:
- 在瘤学瘤学.
- 妇科 妇科 妇科 妇科
- 临床药理学 临床药理学
背景情况:
- 内分泌疗法对雌激素受体阳性乳腺癌至关重要.
- 严重的血管运动症状,如热,往往导致停止治疗.
- 专门的更年期症状诊所为癌症幸存者提供专门的治疗.
研究的目的:
- 在癌症诊所 (MSAC) 后评估专门的更年期症状的利用.
- 为了确定转诊MSAC是否能改善乳腺癌患者的内分泌治疗的坚持,而这些患者有严重的热.
主要方法:
- 对1275名接受内分泌治疗的雌激素受体阳性乳腺癌患者 (2003-2011) 的回顾性分析.
- 对象是指向MSAC的妇女与接受常规治疗严重血管运动症状的妇女之间的长达4年的内分泌治疗坚持.
- 从医院数据库和医疗记录中收集的数据.
主要成果:
- 120名妇女 (9.4%) 被转介给MSAC;147人报告严重的血管运动症状,其中71人被转介给MSAC.
- 通过MSAC管理的严重血管运动症状的妇女的停药率较低 (15.5%),而通常的治疗率 (26.3%).
- 这种坚持差异在统计学上并不显著 (P = 0.1).
结论:
- 在专门的更年期诊所中治疗严重的血管运动症状可能会提高乳腺癌患者的内分泌治疗坚持.
- 专业诊所可以在支持长期癌症治疗合规性方面发挥作用.
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