在ACTIVE中,生命空间流动性和特定领域的认知措施的纵向关联
Emily J Smail1, George W Rebok2,3, Alden L Gross3,4
1Department of Health Outcomes and Biomedical Informatics, University of Florida School of Medicine, Gainesville, FL, USA.
概括
在老年人中,更大的生活空间流动性 (LSM) 与随着时间的推移略有改善的认知功能有关. 然而,LSM并没有显著影响记忆,推理或处理速度认知衰退的速度.
科学领域:
- 老年学是指老年学的学科.
- 认知神经科学 认知神经科学
- 公共卫生 公共卫生
背景情况:
- 生活空间流动性 (LSM) 对于老年人的独立性和福祉至关重要.
- 了解LSM和认知功能之间的关系对于衰老研究至关重要.
研究的目的:
- 为了研究基线生命空间移动性和认知表现之间的纵向关联,在10年的时间内.
- 检查LSM如何影响老年人的记忆,推理和处理速度.
主要方法:
- 在ACTIVE研究中分析了2,690名老年人的数据 (平均年龄为73.0岁).
- 利用多个线性混合效应模型来评估纵向关联.
- 使用生命空间问卷测量LSM和认知表现在八个测试和三个复合分数.
主要成果:
- 未经调整的模型显示了显著的基线LSM对记忆,推理和处理速度的影响.
- 经过调整后,只有一个记忆测试得分仍然与基线LSM有显著关联.
- 较大的基线LSM与略高的认知表现有关,但不是认知变化速度.
结论:
- 基线生活空间流动性显示,与老年人认知表现的联系很弱.
- 在10年内,LSM似乎并没有显著改变认知衰退的轨迹.
- 进一步的研究可能会探索加强LSM及其潜在的认知益处的干预措施.
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