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Updated: Jun 10, 2025

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
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Published on: December 17, 2019

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全基性"现成"CAR T细胞:挑战和进展

Sophia Chen1, Marcel R M van den Brink2

  • 1Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 417 E 68th St, New York, NY, 10065, USA; City of Hope National Medical Center, 1500 E Duarte Rd, Duarte, CA, 91010, USA.

Best practice & research. Clinical haematology
|October 13, 2024
PubMed
概括

异构或"现成"的CAR T细胞疗法为血液癌症患者衍生治疗提供了一个有前途的替代方案. 克服诸如移植与宿主疾病和免疫排斥等挑战是其成功的关键.

关键词:
异构性异构性 异构性化学抗原受体 T 细胞基因编辑 基因编辑移植对宿主疾病 (GVHD) 是一种移植对宿主疾病.免疫系统的排斥 免疫系统的排斥在货架上买的东西.

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