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Updated: Jun 10, 2025

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化剂的目标竞争对手开发无标签和敏感的折叠-解开APTAMER传感器.

Xingli Zeng1, Xiufang Tong1, Jiahui Chen1

  • 1Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Materials Science, Zhejiang Normal University, Jinhua, 321004, Zhejiang, China.

Analytica chimica acta
|October 13, 2024
PubMed
概括

这项研究引入了无标签的折叠-解开的aptamer传感器 (FUAS),比传统方法提供更高的灵敏度. 这些FUAS使用化的目标竞争对手,克服了现有的aptamer传感器的局限性,用于更广泛的应用.

关键词:
柏柏林蛋白是一种柏柏林蛋白.化剂的目标竞争对手可折叠解开的阿普塔默传感器异类类化合物 异类类化合物敏感度 敏感度 敏感度

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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