自杀念头在复发性复发性多发性硬化症的诊断后的一年:一个纵向视角
David C Gillespie1, Riccardo Sacripante2, Siddharthan Chandran3
1Department of Clinical Neurosciences (DCN), Royal Infirmary of Edinburgh, 50 Little France Crescent, Edinburgh, UK, EH16 4TJ; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.
Multiple sclerosis and related disorders
|October 13, 2024
概括
自杀念头在新诊断的多发性硬化症患者中很常见. 早期查至关重要,因为思想持续存在,并与焦虑和抑郁有关.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 自杀念头 (SI) 在长期的多发性硬化症 (MS) 中很普遍.
- 早期MS中SI的流行率,相关因素和时间变化在很大程度上是未知的.
- 了解早期的SI对于新诊断的个体的及时干预至关重要.
研究的目的:
- 确定MS的新诊断后的几周到几个月内SI的患病率.
- 在早期成员国中确定与SI相关的因素.
- 检查SI是否在诊断后的第一年内发生变化.
主要方法:
- 研究了FutureMS队列,这是一个由440名在诊断后几周内复发性缓解性多发性硬化症患者组成的全国样本.
- 自杀念头在基线 (诊断后平均60天) 和12个月后被评估.
- 经过验证的情绪查工具和临床人口统计学变量被用于分析SI及其关联.
主要成果:
- 在基线时,12.8%的个人报告SI,与更大的残疾,焦虑,抑郁,疲劳,所问题和有关.
- 焦虑和抑郁与基线SI显著相关.
- 12个月后,9.6%的人报告SI,与基线相比没有显著变化. 没有任何一个因素预测SI随时间变化.
结论:
- 自杀念头在MS诊断后相对较为常见,即使在轻度抑郁症中也是如此.
- 早期MS中的SI是复杂的,并与各种症状和残疾有关.
- 针对新诊断的MS患者进行SI查对于有针对性的支持至关重要.
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