在患有先天性心脏病的成年人中,中长期的心室辅助器件支持
Ryan D Byrne1, William C Frankel2, Ajith Nair3
1Adult Congenital Heart Program, Department of Pediatrics, Section of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
概括
耐用心室辅助器件为患有先天性心脏病的成年人提供可持续的解决方案,他们面临心力衰竭和长期移植等待时间. 这些设备提供有效的循环支持,并发症不常见,作为移植或目的地治疗的桥梁.
科学领域:
- 心脏病学 心脏病学
- 机械循环支持 机械循环支持
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 心力衰竭是患有先天性心脏病的成年人死亡的主要原因.
- 对这群人来说,心脏移植往往是不可行的,或者需要长时间的等待.
- 持久的机械循环支持提供了潜在的长期解决方案.
研究的目的:
- 评估长期室内辅助器件 (VAD) 治疗在患有先天性心脏病的成年患者中的结果.
- 评估VAD的可行性和可持续性,作为移植或目的地治疗的桥梁.
主要方法:
- 对9名患有先天性心脏病的成年患者 (≥18岁) 的回顾性分析,持续VAD支持≥3年.
- 包括患有多种化的先天性解剖学的患者,包括双心室和单心室 (Fontan循环) 生理学.
- 使用HeartMate 3设备进行机械循环支持.
主要成果:
- 平均支持持续时间为4.2年.
- 三名患者 (33%) 成功过渡到心脏移植,平均等待时间为2.1年.
- 与设备相关的并发症在HeartMate 3设备中并不常见.
结论:
- 耐用心室辅助器械治疗对于患有先天性心脏病的成年人来说是一个可行的和可持续的选择.
- 在这种复杂的患者群体中,VAD可以有效地作为桥梁到移植或目的地治疗.
- 该HeartMate 3设备在患有需要机械循环支持的先天性心脏病的成年人中显示出有利的安全概况.
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