评估与肥胖相关的代谢状况:一种新的客观评分系统更好地告知代谢疾病的严重程度
Victoria Lyo1, John Arriola2, Shushmita M Ahmed1
1Department of Surgery, University of California, Davis, California; Center for Alimentary and Metabolic Sciences, University of California, Davis, California.
新的与肥胖相关的代谢状况评估 (AOMC) 工具更准确地识别了接受减肥手术的患者的代谢疾病严重程度. 这种更新的评分系统揭示了被诊断不足和不受控制的疾病,如糖尿病,高血压和脂质失调.
科学领域:
- 代谢性疾病研究研究.
- 腹腔外科手术的结果
- 临床评估工具 临床评估工具
背景情况:
- 缺乏与肥胖相关的代谢疾病严重程度和对减肥手术的反应的标准化报告.
- 与肥胖相关的代谢状况评估 (AOMC) 工具是为了整合药物治疗和生化数据来评分糖尿病 (DM),高血压 (HTN) 和脂质失调 (DYS) 而开发的.
研究的目的:
- 评估AOMC系统是否提供比现有的临床基础的肥胖相关并发症评估 (AORC) 系统更准确的代谢性疾病严重程度的分期.
主要方法:
- 一项回顾性队列研究利用了从六年来评估减肥手术的成年人的前性收集的人口,临床和生物化学数据.
- 用麦克纳马和威尔科克森的测试来比较AORC和AOMC得分,以确定疾病严重程度的准确性.
主要成果:
- 与AORC相比,AOMC工具发现了更多患有代谢疾病的患者:DM (73.4%与44.5%相比),HTN (91.7%与67.9%) 和DYS (63.8%与53.4%相比).
- AOMC表示,在药物治疗中,较少的患者有足够的疾病控制:DM (39.9%对97.7%),HTN (64.7%对99.3%) 和DYS (51.8%对99.0%).
- 在相当一部分患者中,AOMC:DM (65.9%),HTN (42.9%) 和DYS (30.9%) 增加了疾病的严重程度,揭示了更多的代谢前和严重不受控制的疾病病例.
结论:
- 仅仅临床病史显著低于DM,HTN和DYS的严重程度,突出了对标准化评估工具的需求.
- 该AOMC工具提供了更精确的对代谢性疾病严重程度和对减肥手术的纵向反应的评估.
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