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内脏脂肪指数与肠道习惯和炎症性肠病之间的关联:一个横截面研究
Xiaoxian Yang1, Manli Wang1, Lang Ren1
1Nanjing University of Chinese Medicine, Nanjing, China.
Scientific reports
|October 13, 2024
概括
内脏脂肪指数 (VAI) 与肠道问题有关. 较高的VAI可能会降低慢性便秘的风险,但在较低水平上会增加慢性腹的风险. 健康的睡眠也与便秘的减少有关.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 肥胖是一个全球性的健康问题,内脏脂肪的积累与各种疾病有关.
- 内脏脂肪指数 (VAI) 量化了内脏脂肪,提供了对其健康影响的见解.
- 了解VAI与IBD和改变肠道习惯等胃肠道疾病的关联至关重要.
研究的目的:
- 调查内脏脂肪指数 (VAI) 和肠道习惯 (慢性腹,慢性便秘) 之间的关系.
- 为了检查VAI和炎症性肠病 (IBD) 之间的关联.
- 探索VAI对肠道健康的潜在非线性关系和值影响.
主要方法:
- 利用2005-2010年国家健康和营养检查调查 (NHANES) 数据集进行横截面分析.
- 根据10,391名成年人 (≥20年) 的自我报告数据,定义了肠道习惯和IBD.
- 采用多重物流回归,平滑曲线拟合和值效应分析来评估VAI关联.
主要成果:
- 在同变量调整后,在VAI和慢性便秘之间发现了显著的负相关性 (OR:0.97 [0.95,1.00]).
- 在VAI和炎症性肠病 (IBD) 之间没有观察到显著的关联 (OR:0.97 [0.87,1.07]).
- 确定了VAI和慢性腹之间的非线性关联,断点为VAI=3.08;在这个值以下存在正相关性.
结论:
- 升高的VAI显示出与慢性便秘的负相关性,以及与慢性腹的积极相关性,低于3.08的VAI.
- 保持适度的内脏脂肪水平可能有助于预防慢性便秘和减轻慢性腹风险.
- 健康的睡眠习惯独立地与慢性便秘的风险降低有关.
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