用LC-MS/MS量化人类DNA中的脱氧西瓜诺辛的量化,这是提奥普林治疗优化的标志物

Björn Carlsson1, Louise Karlsson2, Andreas Ärlemalm2,3

  • 1Department of Clinical Pharmacology and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden. bjorn.carlsson@regionostergotland.se.

概括

这项研究开发了一种新方法来测量DNA中结合的硫氨酸,提供了一种更精确的方法来监测治疗白血病和IBD的药物有效性. 这种基于DNA的测量为蒂奥普林药物作用和治疗药物监测提供了更深入的见解.

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