由双半球皮质引起的体感性偏头痛光环在人类皮质皮质中传播抑郁事件
Cedric Gollion1, Rune H Christensen1,2, Håkan Ashina1
1Department of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
概括
偏头痛光环涉及到大脑血流的变化,特别是在发作期间体感皮质. 这些血流变化是双边的,即使光环症状是单边的.
科学领域:
- 神经科学是一个神经科学.
- 医疗成像医学成像
背景情况:
- 皮层扩散抑郁症 (CSD) 与大脑血液流量的改变有关.
- 中枢神经疾病与偏头痛光环的发病有关,但机制尚不清楚.
研究的目的:
- 描述偏头痛发作期间的时空大脑血流变化的特征.
- 为了研究CSD和血液氧气水平依赖 (BOLD) 功能磁共振成像 (fMRI) 反应之间的关系.
主要方法:
- 使用高场功能磁共振成像 (fMRI) 与视觉刺激范式 (闪的棋盘).
- 分析了6名患有偏头痛与自发发作期间光环的参与者的血氧水平依赖 (BOLD) 反应.
主要成果:
- 带有体感症状的光环显示了双边,前后传播的变化,刺激诱导的体感皮质的BOLD反应.
- 这些双边BOLD响应变化发生在没有先前的头异常的情况下,并且独立于光环症状类型 (阳性/阴性).
结论:
- 刺激诱导的BOLD反应的双边异常是偏头痛光环与体感症状的关键发现.
- 这些发现增强了对偏头痛支的神经血管机制的理解.
相关概念视频
Somatosensation
36.4K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.4K
Major Somatic Sensory Pathways
912
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
912
Somatosensory, Motor, and Association Cortex
427
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
427
Overview of Somatic Sensory Pathways
4.2K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.2K


