能量代谢和精子生成
Damilare Emmanuel Rotimi1,2,3, Matthew Iyobhebhe1,2, Elizabeth Temidayo Oluwayemi1,2
1Department of Biochemistry, Landmark University, Omu-Aran, 251101, Kwara State, Nigeria.
Heliyon
|October 14, 2024
概括
男性不孕不育,通常与精子数量低有关,受到葡萄糖代谢的显著影响. 适当的营养和能量基质的可用性对于精子的生产和功能至关重要,影响男性的生殖潜力.
科学领域:
- 生殖生物学 生殖生物学
- 代谢科学 代谢科学
背景情况:
- 男性不孕症影响全球15%的夫妇,精子生产问题是主要原因.
- 葡萄糖代谢对于精子生成和精子细胞生殖潜力至关重要.
- 营养,肥胖和代谢激素显著影响男性生殖功能.
研究的目的:
- 审查男性生殖细胞和塞尔托利细胞的能量代谢.
- 为了强调葡萄糖代谢对男性生育能力的重要性.
主要方法:
- 关于男性生殖细胞和塞尔托利细胞代谢的科学文章的文献综述.
- 分析葡萄糖和乳酸在精子能量生产中的作用.
- 检查影响男性生殖功能的因素.
主要成果:
- 精子细胞直接利用葡萄糖,但依靠塞尔托利细胞获得乳酸.
- 葡萄糖代谢对于精子过度活化的运动性和整体生殖潜力至关重要.
- 精子生物可以在其他能源不可用时使用内部脂质储存.
结论:
- 精子中的葡萄糖吸收和代谢是男性生育潜力的关键指标.
- 了解生殖细胞能量代谢对于解决男性不孕症至关重要.
- 塞尔托利细胞在为生殖细胞提供能量基质方面发挥着至关重要的作用.
更多相关视频
相关概念视频
Spermatogenesis
102.2K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.2K
What is Metabolism?
113.5K
Overview
113.5K
Overview of Metabolism
29.5K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
29.5K
Introduction to Metabolism
1
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
1
Metabolic Rate
288
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
288
Other Glycolytic Pathways
1
The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
1


