在COVID-19在中国爆发之前,期间和之后,急性闭角玻璃眼
Yu Mao1, Yanqian Xie1, Guoxing Li1
1National Clinical Research Center for Ocular Diseases, The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Heliyon
|October 14, 2024
概括
COVID-19 感染增加了急性闭角玻璃眼 (AACG) 病例,特别是在年轻患者中. 潜在的促成因素包括压力,水分和高凝血,突出显示在系统性感染期间需要监测眼睛健康.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 急性闭视角光眼 (AACG) 是不可逆转的视力丧失的主要原因.
- AACG病例的显著增加与中国零COVID政策的放松以及随后的COVID-19疫情相吻合.
- 了解COVID-19和AACG之间的联系对于患者管理至关重要.
研究的目的:
- 为了比较AACG患者在COVID-19爆发之前,期间和之后的人口统计和临床概况.
- 调查将COVID-19感染与AACG发病联系起来的潜在潜在机制.
- 评估COVID-19对AACG发病率和患者特征的影响.
主要方法:
- 一项回顾性比较研究分析了来自第三级眼科医院的连续AACG病例.
- 收集的数据涵盖了流行病前,流行病控制和流行病后的各个阶段,重点关注2022-2023年COVID-19疫情.
- 通过RT-PCR或抗体测试确认了COVID-19感染;在感染和未感染的AACG患者之间比较了眼睛,血清电解质和凝血参数.
主要成果:
- 在2022-2023年的疫情中,有106例AACG病例,明显高于大流行前 (18-22) 和大流行后 (21) 时期.
- 在COVID-19爆发期间,AACG患者年轻,与其他组相比,双边参与的比例更高.
- 64%的爆发AACG患者是COVID-19阳性;在爆发之前报告了抗热药和饮水等因素. 在COVID-19阳性患者中,D-二次体水平较高.
结论:
- 在易受感染的个体中,COVID-19感染似乎会触发AACG.
- 机制可能涉及精神压力,水合,增加胸腔厚度和高凝血.
- 在日常护理和新出现的系统性健康危机期间,眼部健康监测是必不可少的.
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