在诊断和经过治疗时的心电图室内心律不整的参数:一个病例对照研究
Zeynep Zehra Tekin1,2, Hilal Erken Pamukcu3, Serdar Kayihan4
1Etlik City Hospital, Department of Internal Medicine, Varlık Mahallesi, Halil Sezai Erkut Caddesi Yenimahalle, Ankara, Turkey.
Heliyon
|October 14, 2024
概括
壮症患者在治疗后表现出改善的心室心律失常参数,包括Tp-e间隔. 在活跃病例和缓解病例中都观察到这些改善,这表明有效的疾病管理.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 巨症增加了死亡风险,主要是由于心血管并发症.
- 电心电图 (ECG) 参数,如Tp-e间隔,Tp-e/QT和Tp-e/QTc比率是心室心律失常的新兴预测因素.
- 评估这些心电图标记在壮病患者的风险评估至关重要.
研究的目的:
- 在诊断时评估心电图 (ECG) 在壮病患者的发现.
- 为了比较当前的心电图发现与壮病患者的基线测量.
- 为了评估心室再极化参数在壮症.
主要方法:
- 一组103名壮病患者和81名对照人进行了心电图分析.
- 测量了心电图参数,包括心率,QT间隔,纠正的QT (QTc) 间隔,Tp-e间隔,Tp-e/QT和Tp-e/QTc比率.
- 患者被分为基线心电图,当前心电图或两组.
主要成果:
- 在基线和当前心电图的壮病患者显示心率下降,QRS持续时间,Tp-e间隔和Tp-e/QTc比率.
- 这些心律失常参数的改善在活跃和缓解壮症患者中一致.
- 与对照组相比,壮症患者 (基线心电图) 的心率,QTc 间隔,Tp-e 间隔,Tp-e/QT,Tp-e/QTc 均降低.
结论:
- 壮症的治疗导致心室心律失常参数的改善.
- 观察到的改善在活跃和缓解疾病状态之间是一致的.
- 降低IGF-1水平,即使在活跃的疾病中,也可能有助于改善心室再极化.
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