在加纳的一家高等教育医院,在手术感染中使用抗生素
Josephine Mensah1, Antoinette A Bediako-Bowan2, Amos Amoako-Adusei3
1Pharmacy Directorate, University of Ghana Medical Centre, Legon, Accra, Ghana.
Ghana medical journal
|October 14, 2024
概括
抗生素处方率很高,近一半的患者处方包括抗生素. 医生经常根据过去的经验而不是微生物学的结果来选择抗生素.
科学领域:
- 临床药房 临床药房
- 传染性疾病 传染性疾病
- 在外科手术实践中.
背景情况:
- 抗生素处方模式显著影响患者的治疗结果和抗菌素耐药性.
- 了解当前的做法对于制定有针对性的干预措施至关重要.
研究的目的:
- 评估Korle Bu教学医院外科外科的抗生素处方和使用趋势.
- 确定影响手术患者选择抗生素的主要因素.
主要方法:
- 实施了一项横截面研究设计.
- 分析了1715名普通外科,神经外科和泌尿外科病人的处方和病历.
- 对42名处方医生进行了问卷调查.
主要成果:
- 在1715项评估处方中,抗生素被列入了45%的处方.
- 齐普罗夫洛克萨和美特罗尼达在整体手术中很常见;阿莫西西林/克拉夫兰酸和赛夫在神经外科;赛夫和齐普罗夫洛克萨在泌尿病学中很常见.
- 抗生素的选择主要基于处方者以前的经验 (88.1%),仅限于培养和敏感性测试 (14.5%的住院患者).
结论:
- 在手术部门,抗生素的使用量很大.
- 处方决策在很大程度上受到实证知识的影响,而不是实验室诊断.
- 需要促进准则的遵守和微生物学测试,以优化抗生素的使用.
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