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从S-化粉合成一种生物活性氧化释放聚合物

Jéssica Fernanda da Silva¹, Edson Araujo de Almeida², Geovana Ellen Karoleski³

¹Food Engineering Course, Federal Technological University of Paraná (UTFPR), Campo Mourão Campus, Campo Mourão 87301-899, Paraná, Brazil.

|October 14, 2024

概括

研究人员开发了一种具有可控释放特性的新型氧化释放聚合物 (BioNOR-P). 这种生物活性物质具有杀菌和抗氧化活性,为先进的应用铺平了道路.

科学领域:

生物材料科学生物材料科学
聚合物化学聚合物化学
医疗器械医疗器械

背景情况:

将氧化 (NO) 纳入聚合物增强了稳定性,并使控制释放成为可能.
无释放聚合物的应用范围包括医疗用,食品包装和可植入设备.

研究的目的:

开发一种经济且简单的方法来制造生物活性氧化释放聚合物 (BioNOR-P).
评估开发的BioNOR-P.的杀菌,抗氧化,机械,细胞毒和基因毒性质.

主要方法:

生物NOR-P薄膜是使用造方法制造的.
氧化释放动力学是在水性介质中测量.
评估了抗氧化活性,机械性能,细胞毒性和基因毒性.

主要成果:

造方法产生了一种具有良好的机械特性的均,透明的BioNOR-P薄膜.
该膜表现出一个持续的氧化释放率为0.58nmol/g−1min−1.1.
该物质表现出非细胞毒性,显著的抗氧化活性和有效的细菌生长抑制.

结论:

开发的BioNOR-P为氧化物输送提供了一个有前途的平台,在各种应用中具有潜力.
该材料的特性支持其在需要抗微生物和抗氧化功能的领域的未来使用.

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