AIBP通过抑制MAPK介导的NR4A1表达来保护药物诱导的肝损伤

Tao Ma1,2, Wei Huang1, Yihong Ding1,3

  • 1Department of Gastroenterology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.

iScience
|October 14, 2024
PubMed
概括

脂蛋白A-I结合蛋白 (AIBP) 能够防止药物诱导的肝损伤 (DILI). 较低的AIBP水平会恶化肝损伤,而较高的AIBP水平则通过抑制MAPK通路提供保护.

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