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儿童结核病诊断的MTB/RIF Ultra:来自国家扩展计划的经验

S Kabir¹, S Choudhury¹, T Rahman¹

¹Progamme on Emerging Infections, Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

|October 14, 2024

概括

使用Xpert MTB/RIF Ultra的便检测显著改善了儿科肺结核的诊断. 这种方法可以识别更多的病例,但诊断产量因症状而异,需要仔细评估以获得最佳的资源使用.

科学领域:

微生物学微生物学
公共卫生公共卫生
儿童传染病儿童传染病

背景情况:

世界卫生组织建议Xpert MTB/RIF Ultra (Ultra) 用于改善儿童肺结核 (PTB) 诊断.
使用Ultra进行便测试的程序化扩展对于提高儿童PTB检测至关重要.

研究的目的:

评估Xpert MTB/RIF Ultra用于诊断儿童肺结核的便检测的有效性.
评估各种医疗保健机构的便超检测的程序性实施和诊断产量.

主要方法:

在孟加拉国51个医疗机构实施了使用Xpert MTB/RIF Ultra的基于便的诊断方法.
测试了儿童 (<15岁) 假定结核病的样本,医生证实了结核病的诊断和治疗.

主要成果:

在2022年3月至2023年12月期间,测试了超过16,400个标本,阳性率为5.3%.
很大一部分 (73.7%) 的阳性结果是"痕迹检测".
阳性因年龄,性别和出现症状而异,女性和特定症状集群的比率更高.

结论:

使用Ultra的便检测提供了一种更有效的方法来诊断细菌学确认的儿童PTB.
诊断产量受症状的影响,强调需要明智地应用诊断资源.

关键词:

孟加拉国孟加拉国孟加拉国在Xpert MTB/RIF Ultra中使用.诊断诊断诊断诊断诊断诊断高结核病负担的国家这是一种非侵入性的非侵入性治疗方法.儿童结核病儿童结核病结核病是一种肺结核病.

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