对影响术后 keloid 痕复发复发风险因素的逻辑回归分析
1Department of Plastic Surgery, The First Affiliated Hospital of Wannan Medical College No. 2, Ocheshan West Road, Yijishan Street, Jinghu District, Wuhu 241001, Anhui, China.
American journal of translational research
|October 14, 2024
概括
手术后的状痕复发受感染,家族病史,痕大小以及缺乏放射治疗或激素治疗的影响. 识别这些危险因素有助于预测和潜在地防止 keloid 痕再次出现.
科学领域:
- 皮肤病学和整形外科
- 医学研究 医学研究
- 临床流行病学临床流行病学
背景情况:
- 状体痕可能在手术切除 (状体切除术) 后复发.
- 识别 keloid 痕复发的风险因素对于改善患者的治疗结果至关重要.
- 预测模型可以帮助管理容易发生 keloid 复发的患者.
研究的目的:
- 为了确定手术后质痕复发的独立风险因素.
- 使用后勤回归开发一个预测模型,用于 keloid 痕复发.
- 评估已识别的风险因素的预测性能.
主要方法:
- 追溯分析了132名接受带切除术的患者.
- 后勤回归分析以确定复发的独立风险因素.
- 接收器操作特征 (ROC) 曲线和Nomogram生成用于预测性能.
主要成果:
- 在28.79%的患者中观察到状痕复发.
- 确定了独立的风险因素:感染,家族病史,较大的痕大小,没有放射治疗/局部激素治疗.
- 预测模型以高准确度实现了0.889的ROC曲线下的面积.
结论:
- 感染,家族病史,较大的痕大小和缺乏辅助疗法是 keloid 痕复发的重要危险因素.
- 鉴定出来的因素为手术后胆固醇复发的预测模型提供了基础.
- 这些发现可以为临床管理策略提供信息,以减少 keloid 痕的复发.
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