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Updated: Jun 10, 2025

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过氧体进口压力激活了综合应激反应,并抑制了核糖体生物发生

Jinoh Kim1, Kerui Huang1, Pham Thuy Tien Vo1

  • 1Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, IA 50011, USA.

PNAS nexus
|October 14, 2024
PubMed
概括

缺陷的过氧体蛋白进口激活了综合应激反应 (ISR) 并抑制了核糖体生物发生. 这种由ATF4介导的细胞应激反应保护细胞免受损伤,并影响rRNA处理.

关键词:
在PEX5中使用PEX5早期的rRNA处理综合应激反应综合应激反应过氧体进口应激压力核糖体生物发生的生物.

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