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Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
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局部麻醉剂在怀孕期间的系统性毒性:回顾性队列分析

Micah K De Valle1, Michael Adkison1, Ruhi Maredia1

  • 1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, USA.

Cureus
|October 14, 2024
PubMed
概括

与非孕妇相比,患有局部麻醉系统毒性 (LAST) 的孕妇表现出明显的症状,心脏抑郁的风险更高,刺激或前兆效应的迹象较少.

关键词:
心血管毒性心血管毒性局部镇痛 局部镇痛 局部镇痛局部麻醉剂系统性毒性 (最后一个)神经毒性的作用.产科麻醉 产科麻醉周周的时间是周周的时间.怀孕的风险 怀孕的风险怀孕的女性 孕妇

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While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
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