相关实验视频
Updated: Jun 10, 2025

10:42
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
17.1K
口腔微生物对儿童呼吸道感染的影响
Alexandra Mihaela Crestez1,2, Aurel Nechita1,2, Miruna Patricia Daineanu1,2
1Pediatric Department, "Sf. Ioan" Emergency Clinical Pediatric Hospital, Galați, 800494, România.
Pediatric health, medicine and therapeutics
|October 14, 2024
概括
儿科呼吸道微生物组会影响感染的易感性和严重性. 保持微生物平衡是预防儿童复发性呼吸道感染 (RTIs) 的关键.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
背景情况:
- 呼吸系统内含着动态的细菌微生物群,影响免疫力,特别是在儿科呼吸道感染中.
- 关键的细菌如*Streptococcus pneumoniae*,*Moraxella catarrhalis*和*Haemophilus influenzae*在儿童中普遍存在,并影响呼吸道感染 (RTIs).
研究的目的:
- 评估上呼吸道微生物对儿科呼吸道感染易感性和严重性的影响.
- 了解早期的细菌殖民,包括*Moraxella*和*Streptococcus*,如何影响从出生到青春期的RTIs.
主要方法:
- 2004年至2023年间发表的研究文献综述.
- 专注于儿科人口 (出生至18岁),微生物特征,免疫反应调制和微生物组向干预.
主要成果:
- 上呼吸道微生物组的组成和破坏显著影响儿科呼吸道感染的临床结果.
- 微生物组失调与增加对复发感染的易感性有关,强调了微生物平衡的必要性.
结论:
- 了解口腔和上呼吸道微生物群可以改善儿童呼吸道感染的管理和预防.
- 微生物组调制,可能使用益生菌,显示了改善儿科RTIs临床结果的希望.
相关概念视频
Factors Affecting the Risk of Infection
11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K
Anatomy of Respiratory System I: Upper Respiratory Tract
1.2K
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
1.2K
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
235
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
235
Factors Affecting Pulmonary Ventilation
1.2K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.2K
Other Pulmonary Disorders
806
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
806
Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K

