关于老年患者术后认知功能障碍的当前观点:从临床实践的见解
Liang Zhang1, Yi Qiu1, Zhi-Feng Zhang2
1Department of Anaesthesiology, The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Frontiers in medicine
|October 14, 2024
概括
手术后认知功能障碍 (POCD) 影响手术后的老年患者. 术前优化,仔细选择麻醉剂和康复等策略可以减少POCD发生率并改善患者的治疗结果.
科学领域:
- 老年医学 老年医学
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
背景情况:
- 手术后认知功能障碍 (POCD) 是老年手术患者的普遍并发症.
- POCD显著影响认知功能和生活质量.
- 它的复杂病理生理学涉及衰老,手术/麻醉因素,神经炎症和遗传学.
研究的目的:
- 审查目前在老年患者中预防和管理POCD的策略.
- 突出新兴的治疗和非药物干预措施.
- 概述POCD的未来研究方向.
主要方法:
- 对POCD病理生理学和管理研究的文献综述.
- 对手术前,手术内和手术后的干预措施的分析.
- 对药理学和非药理学方法的评估.
主要成果:
- 术前优化,适当的麻醉,微创手术和早期康复是有效的.
- 抗炎和神经保护剂显示有前途.
- 认知和体育训练干预措施产生了积极的影响.
结论:
- 综合各种策略的多学科方法是减少POCD的关键.
- 需要进一步的大规模试验和机制研究.
- 医疗保健专业人员的持续教育对于有效的POCD管理至关重要.
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