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A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
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针对癌症引起的骨疼痛的新疗法

Rayan Haroun1, Samuel J Gossage1, Federico Iseppon1

  • 1Molecular Nociception Group, Wolfson Institute for Biomedical Research (WIBR), University College London (UCL), London WC1E 6BT, United Kingdom.

Neurobiology of pain (Cambridge, Mass.)
|October 14, 2024
PubMed
概括

针对神经生长因子 (NGF) 和瘤坏死因子 (TNF) 等炎症媒介,在临床前模型中有效降低了癌症诱导的骨疼痛 (CIBP). 对NGF和TNF的双重抑制显示出对CIBP治疗具有优越的止痛作用.

关键词:
酸感应离子通道的离子通道癌症引起的骨头疼痛是癌症引起的.背部根结腺细胞.修改的肉化合物 修改的肉化合物神经生长因子的神经生长因子瘤亡因子α因子电压关闭通道的通道

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