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Updated: Jun 10, 2025

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

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骨质素与GPRC6A金星虫捕捉器的全位结合,以积极调节GPRC6A信号传输

Rupesh Agarwal1,2, Ruisong Ye3, Micholas Dean Smith1,2

  • 1Oak Ridge National Laboratory Center for Molecular Biophysics University of Tennessee Oak Ridge Tennessee USA.

FASEB bioAdvances
|October 14, 2024
PubMed
概括

骨素 (Ocn) 作为GPRC6A的正调节器 (PAM),GPRC6A是一种参与新陈代谢和激素产生的受体. 这一发现阐明了多种连接物如何激活GPRC6A,从而使新的药物开发成为可能.

关键词:
G蛋白结合受体 (GPCR) 是一种受体.在 GPRC6A 中.细胞外域是细胞外域.同源性建模的同源性建模异形选择性 - 异形选择性突变发生的突变发生.负基调节器是负基调节器骨质卡尔辛是一种骨质卡尔辛.阳性全osteric 调节器是正性的.

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