甲状腺癌中的血清水平:一个病例对照研究
Saeed Dahmardeh1, Zahra Heidari1
1Department of Endocrinology and Metabolism, Zahedan University of Medical Sciences, Zahedan, Iran.
Medical journal of the Islamic Republic of Iran
|October 14, 2024
概括
低水平与乳头甲状腺癌 (PTC) 有关. 更高的癌症阶段显示的减少. 可能在甲状腺癌的发展中起着保护作用.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 尽管补充,甲状腺疾病仍然很普遍.
- 微量元素如在甲状腺健康中的作用需要研究.
研究的目的:
- 检查血清水平与乳头甲状腺癌 (PTC) 之间的关联.
- 为了比较PTC患者,良性甲状腺结节和健康对照者的水平.
主要方法:
- 一项涉及182名PTC患者,185名良性结节患者和180名健康对照者的病例控制研究.
- 评估甲状腺功能测试和血清水平.
- 使用单向ANOVA和邦费罗尼校正的统计分析.
主要成果:
- 与良性结节 (121.6μg/l) 和对照组 (134.3μg/l) 相比,PTC患者的平均血清水平显著降低 (94.9μg/l).
- 在PTC患者中,较低的水平与晚期癌症相相关 (P < 0.001).
- 的每一个单位增加将PTC的几率降低约6%.
结论:
- 低血清水平与乳头甲状腺癌的风险增加有关.
- 血清水平与甲状腺癌的阶段相反相关.
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