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Updated: Jun 10, 2025

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德科维里马特抗病毒活性和毒素病毒抗性的机制

Riccardo Vernuccio1, Alejandro Martínez León2, Chetan S Poojari2

  • 1G5 Structural Biology of Infectious Diseases, Institut Pasteur, Université Paris Cité, Paris, France.

Research square
|October 14, 2024
PubMed
概括

一种mopox病毒药物Tecovirimat通过迫使病毒脂酶F13进行二元化而起作用. 导致药物耐药性的突变发生在这个二元化部位,影响治疗的有效性.

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